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7 Most Trending Frameworks for Building Multi-Agent AI Applications

Artificial intelligence (AI) has come a long way, from AI assistants to chatbots to complex agents. With the rapid increase in AI technology, businesses need AI systems where multiple specialized agents work together. Creating these sophisticated multi-agent applications for real-world use can be more complicated than you think, with interactions, data, and deployment management, and it demands powerful tools. Thankfully, several frameworks have emerged to simplify this process. They offer developers structured ways to build, test, and run coordinated AI agent teams. In this article, we'll check out these top 7 best key frameworks that let you build multi-agent AI apps ready for production.


Here are the top 7 best frameworks for building multi-agent AI apps ready for production:



Motia is an AI agent framework specifically built for software engineers, allowing them to write agent components in different programming languages. Python, TypeScript, and Ruby can work together within a single agent workflow. This flexibility means teams can use the languages they already know well.


Motia focuses on event-driven automation, which means running tasks efficiently with little system load. Developers can watch their agents operate in real-time using visual tools. The framework also includes tools to deploy applications with a single command. A cloud service, Motia Hub, handles the backend infrastructure needed to run agents, simplifying scaling and managing agents in production environments.


  • Multi-Language Compatibility: Use Python, TypeScript, and Ruby in one agent.

  • Built-in Observability: Visualize agent activity and logs with Motia Workbench.

  • Instant APIs and Scheduling: Easily create web endpoints for agents and schedule tasks.

  • Zero Infrastructure Setup (via Motia Hub): Deploy agents without managing complex backend systems.


2. Agno


Agno offers a lightweight approach to building AI agents, focusing on equipping them with memory, knowledge access, and reasoning tools. Developers use it to create individual reasoning agents or coordinate teams of agents. Agno claims significantly faster performance compared to some alternatives like LangGraph. It also uses much less memory, making it efficient.


The framework includes a user interface for chatting with agents, and tools for monitoring agent sessions and performance are also provided. Agno supports various AI models and integrates with numerous vector databases for knowledge retrieval. This helps agents access relevant information for their tasks.


  • Lightning Fast: Very quick agent startup times and low memory usage.

  • Natively Multi-modal: Agents can process and generate text, images, audio, and video.

  • Advanced Multi-Agent Architecture: Supports different modes for agent collaboration and coordination.

  • Monitoring: Track agent sessions and performance in real-time.



Coming from the creators of the popular Pydantic library, Pydantic AI aims for production readiness. Its main strength is in handling structured data outputs from AI models. This feature helps avoid common problems when getting predictable results from language models. The framework is designed to work with different AI models easily.


Its flexibility saves time if developers need to switch models later. Pydantic AI emphasizes a good developer experience, reflecting its open-source roots. While focused on agents, it connects with tools like Logfire for observability. This framework is suited for Python developers needing reliable data handling in AI apps.


  • Structured Outputs: Simplifies getting predictable, structured data from AI models.

  • Model-agnostic design: Easily switch between different underlying language models.

  • Production-Ready Focus: Built with stability and real-world applications in mind.

  • Developer Experience: Prioritizes ease of use, drawing from Pydantic's principles.



Amazon Web Services (AWS) offers this open-source framework for managing complex AI conversations. It is great at routing user queries to the most appropriate agent. This smart routing prevents confusion when multiple specialized agents are involved. The framework is fully available in both Python and TypeScript.


It supports different response types, allowing some agents to stream replies while others don't. Context management is key, ensuring conversations remain coherent across multiple agent interactions. Developers can run this framework anywhere, including AWS Lambda or other cloud platforms, as it comes with pre-built agents and classifiers to speed up development.


  • Intelligent Query Routing: This directs user input to the best-suited agent dynamically.

  • Dual Language Support: Full implementations in both Python and TypeScript.

  • Context Management: Maintains conversation history across different agents.

  • Universal Deployment: It can run on AWS services, other clouds, or locally.



AutoAgent targets users who need to build AI agent systems quickly without writing code, allowing users to create entire multi-agent teams using only natural language prompts. This significantly speeds up the development process for certain use cases. AutoAgent features a built-in, self-managing vector database for agent knowledge.


The creators claim this database performs better than some common alternatives. The framework supports a wide variety of large language models (LLMs). It offers flexibility in how agents interact, supporting both function-calling and ReAct methods. AutoAgent aims to be a dynamic and customizable tool for non-programmers.


  • No-Code Agent Building: Create agents and workflows using natural language instructions.

  • Native Self-Managing Vector Database: Built-in knowledge storage solution.

  • Universal LLM Support: Works with models from OpenAI, Anthropic, Huggingface, and others.

  • Flexible Interaction Modes: Supports both function-calling and ReAct approaches.



OpenAI provides this software development kit for building agentic applications, focusing on simplicity and using minimal core concepts. The main building blocks are Agents (LLMs with instructions and tools) and Handoffs. Handoffs allow one agent to delegate tasks to another effectively.


The SDK also includes Guardrails for validating agent inputs. Because it's Python-first, developers can use standard Python code for orchestration. This avoids needing to learn many new, complex abstractions. Built-in tracing helps visualize, debug, and monitor agent workflows. This tracing also integrates with OpenAI's evaluation and fine-tuning tools.


  • Python-First: Leverage standard Python for agent coordination.

  • Handoffs: A core feature for managing delegation between agents.

  • Guardrails: Built-in capability to check and validate agent inputs.

  • Built-in Tracing: Visualize, debug, and monitor agent activity easily.



Google's open-source ADK framework focuses on end-to-end agent development and is designed to build single agents and complex multi-agent systems. The framework integrates tightly with the Google Cloud ecosystem, including Gemini models and Vertex AI.


ADK allows the creation of hierarchical agent structures where tasks can be delegated, making it well-suited for building collaborative agent teams. Developers can use pre-built examples from the Agent Garden. Google offers Agent Engine, a managed runtime on Vertex AI for deployment, as it can handle scaling, testing, and production agents' reliability.


  • Google Ecosystem Integration: Designed for use with Gemini models and Vertex AI.

  • Multi-Agent System Focus: Strong support for hierarchical structures and task delegation.

  • Extensible Sample Agents: Access readily available examples in Agent Garden.

  • Managed Runtime Option: Deploy agents reliably using Agent Engine on Vertex AI.


Conclusion:


Building applications where multiple AI agents collaborate is becoming more feasible and more important for businesses now than ever before. Frameworks like Motia, Agno, Pydantic AI, AWS Multi-Agent Orchestrator, AutoAgent, OpenAI Agents SDK, and Google ADK provide essential structures for building multi-agent AI production apps. They address key challenges in development, management, and deployment. The best part is that these tools are expected to mature and become more sophisticated and reliable multi-agent systems entering the mainstream business world. Choosing the appropriate framework is the important first step for organizations that are aiming to build advanced AI capabilities.

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